Microbiological testing for antiplaque ingredients recommended by FDA Plaque Subcmte..
This article was originally published in The Rose Sheet
Executive Summary
MICROBIOLOGICAL TESTING FOR ANTIPLAQUE INGREDIENTS would be required as part of a company's safety data submission to FDA under a recommendation from the agency's OTC Plaque Subcommittee. In changes made to a "points to consider" document on how to determine safety and effectiveness of antiplaque products, the subcommittee said it is concerned with "the potential of antiplaque ingredients with antimicrobial effects to induce resistance in oral microorganisms or allow an oral overgrowth of inherently resistant potential pathogens."