In Brief: Galderma Differin -vs- J&J Retin-A
This article was originally published in The Rose Sheet
Executive Summary
Galderma Differin -vs- J&J Retin-A: Results from three Galderma studies comparing the irritation potential of Differen (adapalene .1%) in different gel vehicles with Retin-A (tretinoin gel .025%) found that adapalene gel "was very well tolerated when applied topically in standard cumulative irritation tests" and was relatively non-irritating when used on facial skin. Tretinoin under similar testing conditions "produced severe irritation reactions resulting in treatment discontinuation in many cases," according to the Galderma researchers. Galderma's analysis of two large multi-centered Phase I trials on the safety and efficacy of the two ingredients concluded that the 295 tretinoin users in both studies combined reported higher numbers of cutaneous events that the 296 adapalene users. Galderma has an NDA pending for adapalene 1%, a naphtholic acid derivative...
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Marketing In Brief
ModiFace launches forecasting tool: Toronto-based virtual makeover firm introduces ShadeCast, a makeup sampling and forecasting tool based on behavioral tracking. ShadeCast is used in conjunction with iPhone application MakeUp, which allows consumers to virtually try on makeup in hundreds of shades from brands including Revlon, Cover Girl, Lancome and Clinique. ShadeCast offers 1,000 cosmetic shades from 40 brands and assigns a ShadeScore "to approximately position the [app's] hottest and most sampled color." ModiFace exec Nikkie Gatto likens the app to radio music playlists, helping consumers "looking to capture the current look, but also provide vital market intelligence to our retail channel partners," she says in Nov. 3 release. "The value of data to demonstrate the aggregate behavior will help the industry predict the latest trends and help cosmetic manufacturers better understand the color and products which most resonate with online and iPhone virtual makeover users," the company says