HBW Insight is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


In Brief: Retin-A and stretch marks

This article was originally published in The Rose Sheet

Executive Summary

Retin-A and stretch marks: Study sponsored by J&J published in the May issue of the American Medical Association's Archives of Dermatology concludes that "topical application of tretinoin significantly improves the clinical appearance of early, active stretch marks." The study, conducted by Sewon Kang, MD, University of Michigan Medical Center Department of Dermatology, et al., examined the effects of .1% tretinoin cream on 10 subjects compared to 12 subjects, who received a placebo treatment. After six months, eight Retin-A patients "had marked improvement," with stretch mark length decreases of 14% and width decreases of 8% versus increases in length and width of 10% and 24%, respectively for the placebo group. Only one placebo patient showed improvement, the study states. Kang et al. noted in the study that "the processes that are responsible for the clinical improvement remain unknown." Another University of Michigan study focusing on Retin-A as a treatment for photo-aged skin formed the basis of an off-label promotion campaign for the acne treatment that prompted an FDA/Department of Justice investigation of J&J ("The Rose Sheet" Jan. 16, 1995, p. 1)...



Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts