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Ocular Irritation Test Recommendations Outlined By ICCVAM

This article was originally published in The Rose Sheet

Executive Summary

Optimization and validation studies using a standardized test method protocol should be conducted before four in vitro test methods evaluating severe eye irritants and corrosives are routinely used for regulatory hazard classification and labeling in a regulatory tiered testing strategy, the Interagency Coordinating Committee for the Validation of Alternative Methods says

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ICCVAM Ocular Irritation Reanalyzed Data Published For Comment 

The Interagency Committee on the Validation of Alternative Methods is seeking comments on revised background review documents on four in vitro ocular alternative tests, the agency announced in a July 25 Federal Register notice

ICCVAM Ocular Irritation Reanalyzed Data Published For Comment 

The Interagency Committee on the Validation of Alternative Methods is seeking comments on revised background review documents on four in vitro ocular alternative tests, the agency announced in a July 25 Federal Register notice

Ocular Irritation Assay Data Deemed Incomplete By ICCVAM Panel

Existing data are inadequate to determine whether the Isolated Rabbit Eye test method can identify severe ocular irritants or corrosives under a tiered testing strategy, the Interagency Coordinating Committee on the Validation of Alternative Methods expert panel concluded during a Jan. 11-12 meeting in Bethesda, Md

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