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Animal alternative tests

This article was originally published in The Rose Sheet

Executive Summary

Interagency Coordinating Committee on the Validation of Alternative Methods posts additional data on Hen's Egg Test - Chorioallantoic Membrane on its Web site Nov. 16. Addendum includes in vitro data for substances tested in CEC, in vitro and in vivo comparison of ocular irritancy classification of substances tested in CEC and in vivo and in vitro comparison of ocular irritancy classification, data sorted by substance for IS(B) analysis method. The National Interagency Center for the Evaluation of Alternative Toxicological Methods and ICCVAM recently posted draft background review documents on four alternative ocular irritancy tests, including HET-CAM, Bovine Corneal Opacity and Permeability, Isolated Chicken Eye and the Isolated Rabbit Eye (1"The Rose Sheet" Nov. 15, 2004, p. 5). Agencies are seeking comments on the documents by Dec. 30, which will be addressed during a meeting Jan. 11-12 in Bethesda, Md...
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