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P&G dandruff study

This article was originally published in The Rose Sheet

Executive Summary

Zinc contained in pyrithione zinc anti-dandruff formulas is not inert, but rather improves the efficacy of the complex when adequately partnered with pyrithione, leading to improved PTZ formulation technology, according to Procter & Gamble. The company says it previously believed pyrithione alone was active in PTZ. Conducted by P&G researchers including James Schwartz, PhD, findings build on a prior P&G study that identified Malassezia globosa as the exact fungal species that causes dandruff. The new study, which further explored the mechanism by which PTZ fights Malassezia, found that PTZ's "bioavailability and antifungal activity is maximized by preventing PT from dissociating from the zinc ion during treatment," the firm claims. The findings have not been published, and P&G would not comment on plans to do so in the near term...
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