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This article was originally published in The Rose Sheet

Executive Summary

Interagency Coordinating Committee for the Validation of Alternative Methods issues second expert panel report on its assessment of the current validation status of in vitro test methods for identifying ocular corrosives and severe irritants, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods announces in Nov. 2 Federal Register 1notice. The report is the product of an ICCVAM teleconference Sept. 19, in which the panel reanalyzed background review documents on the methods, but made similar conclusions to those it reached during its January meeting (2"The Rose Sheet" Sept. 26, 2005, In Brief). The background review documents were initially released in July on Isolated Rabbit Eye, Isolated Chicken Eye, Bovine Corneal Opacity and Permeability and Hen's Egg Test - Chorioallantoic Membrane (3"The Rose Sheet" Aug. 1, 2005, p. 9). NICEATM is requesting comments on the second expert report by Dec. 2...

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