HBW Insight is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

ICCVAM

This article was originally published in The Rose Sheet

Executive Summary

Interagency Coordinating Committee for the Validation of Alternative Methods issues second expert panel report on its assessment of the current validation status of in vitro test methods for identifying ocular corrosives and severe irritants, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods announces in Nov. 2 Federal Register 1notice. The report is the product of an ICCVAM teleconference Sept. 19, in which the panel reanalyzed background review documents on the methods, but made similar conclusions to those it reached during its January meeting (2"The Rose Sheet" Sept. 26, 2005, In Brief). The background review documents were initially released in July on Isolated Rabbit Eye, Isolated Chicken Eye, Bovine Corneal Opacity and Permeability and Hen's Egg Test - Chorioallantoic Membrane (3"The Rose Sheet" Aug. 1, 2005, p. 9). NICEATM is requesting comments on the second expert report by Dec. 2...

You may also be interested in...



ICCVAM

Interagency Coordinating Committee for the Validation of Alternative Methods likely will issue a draft report on four in vitro tests for detecting ocular corrosives and severe irritants to benefit downstream users, despite the fact the document will contain similar conclusions to separate background review documents released in 2004, NICEATM Deputy Director Raymond Tice, PhD, says during a Sept. 19 teleconference. ICCVAM expert panel meeting addressed reanalyzed data on the four tests - Isolated Rabbit Eye, Isolated Chicken Eye, Bovine Corneal Opacity and Permeability and Hen's Egg Test - Chorioallantoic Membrane, which were released in July (1"The Rose Sheet" Aug. 1, 2005, p. 9). However, panel's conclusions were largely unchanged from those expressed during its January meeting (2"The Rose Sheet" Jan. 17, 2005, p. 4). Agency should undertake "some kind of critical review to see whether or not it's worthwhile moving forward" with reviews of HET-CAM and ICE, according to panel member Roger Beuerman, PhD...

ICCVAM Ocular Irritation Reanalyzed Data Published For Comment

The Interagency Committee on the Validation of Alternative Methods is seeking comments on revised background review documents on four in vitro ocular alternative tests, the agency announced in a July 25 Federal Register notice

Bristol/Exelixis Detail Survival Benefit For Opdivo/Cabometyx In Renal Cancer

Data show Opdivo/Cabometyx combo bests Sutent for overall and progression-free survival and response endpoints in first-line RCC. Exelixis CEO says comparison to Sutent is standard control and allows better comparison to other combo regimens.

UsernamePublicRestriction

Register

LL1133833

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel