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ICCVAM panel report

This article was originally published in The Rose Sheet

Executive Summary

National Toxicology Program Interagency Center on Evaluation of Alternative Toxicological Methods is requesting comments on a report by Interagency Coordinating Committee on the Validation of Alternative Methods scientific peer review panel regarding the 3T3 mouse fibroblast test and the normal human keratinocyte method, agency says in July 11 Federal Register notice. Report contains conclusions from May 23 meeting, including recommendation that the in vitro cytotoxicity test methods are sufficient for use in a weight-of-evidence approach to determine the starting dose for acute oral in vivo toxicity testing (1"The Rose Sheet" May 29, 2006, p. 8). Comments are due Aug. 25...

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