CIR’s Draft Ingredient List For 2015 Review Raises No Red Flags
This article was originally published in The Rose Sheet
The CIR Expert Panel released its draft list of 22 cosmetic ingredients/ingredient groups targeted for review in 2015, all low-hazard substances according to the Environmental Working Group’s Skin Deep website. CIR introduced the draft roster ahead of schedule to allow more time for public input, and will issue a final priority list in June.
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CIR adds hair-dye ingredient 1-hydroxyethyl-4,5-diamino pyrazole sulfate and conditioning agent hydrolyzed keratin to its 2015 priority review list, which was approved during the Expert Panel’s June 9-10 meeting in Washington D.C. The panel issued final safety reports for seven ingredients and gave tentative final reports for eight substances.
Cosmetic Ingredient Review’s Infant Resource Document provides the organization’s perspective on neonatal and infant skin and chemical absorption risks to guide the CIR Expert Panel’s future reviews and development of related reports. Generally, the group believes the stratum corneum is an effective barrier in infants at or around birth, but infants’ ability to metabolize chemicals versus that of adults is not as well understood, according to the draft document, which the panel will review at its meeting in June.
CIR may take counter position to Europe in determining that preservative methylisothiazolinone can safely be used in leave-on personal care products, panel members suggested during March 17-18 meeting in Washington D.C. Review of the ingredient is tabled until the panel receives new sensitization data.