CIR Panel Looks To Establish Guidelines For Read-Across Use
This article was originally published in The Rose Sheet
At its December meeting in Washington, the Cosmetic Ingredient Review Expert Panel finalized safety assessments for eight ingredients and advanced three other reports. In its reviews, the group made selective use of read-across data while agreeing to discuss protocol for employing the predictive approach in future reviews.
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Chart: Data compiled by the Rose Sheet from information in CIR reports and the panel’s Dec. 5-6 meeting.
While FDA has gone on record as being leery of proposed legislation that would formalize its relationship with the Cosmetic Ingredient Review, the agency continues to leverage the industry-funded program’s expertise. At FDA’s request, the CIR Expert Panel will review progressive hair dye lead acetate in 2017.
ECHA's progress report on REACH evaluations conducted in 2015 identifies priority targets in its compliance checks and common shortcomings in registrants' dossiers. With new animal testing under the microscope, the agency provides guidance on using (Q)SARs to fill data gaps, as well as insight into its approach to assessing read-across, to assist companies readying for the May 31, 2018 registration deadline.