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N-9 Data Warrants Spermicide Safety Study, WHO Report Recommends

This article was originally published in The Tan Sheet

Executive Summary

The safety of all spermicides should be evaluated in light of recent research indicating the one-time top microbicide candidate nonoxynol-9 actually causes lesions that may facilitate transmission of HIV and other sexually transmitted infections, according to the final report of a "Technical Consultation on N-9," released June 25

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CondomDepot.com drops N-9

CondomDepot.com claims to be the first major condom retailer to stop selling products containing the spermicide nonoxynol-9 in Feb. 26 announcement. "Studies prove that the small amount of nonoxynol-9 used on condoms has been declared ineffective as a contraceptive and does not substantially decrese the incidence of pregnancy," CondomDepot.com president Kimberly Fidi states. "Condoms alone are 98% effective when used properly," she adds. Concern surrounding N-9's use is due in part to a 2002 World Health Organization report that the spermicide was an irritant and could possibly facilitate HIV transmission and other sexually transmitted diseases (1"The Tan Sheet" July 8, 2002, p. 17)...

Durex nixes nonoxynol-9

Condom marketer will discontinue the use of the spermicide nonoxynol-9 in manufacturing its Durex condom line due to an anticipated "material reduction in demand for spermicidally lubricated condoms," SSL International announces recently. The decision follows a report by the World Health Organization "which questioned the level of additional protection provided by such condoms when compared to non-spermicidally lubricated condoms," London-based company says. The WHO's June 2002 report also recommended evaluating the safety of spermicides following research that showed their use may increase the risk of STD transmission (1"The Tan Sheet" July 8, 2002, p. 17)...

Microbicide Trial “Condom Only”-Arm Designs To Be Reviewed By FDA Cmte.

FDA is seeking guidance from the Antiviral Drugs Advisory Committee as to whether clinical trials on topical microbicides should include a "no treatment" (condom only) arm

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