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Ephedrine/Caffeine Combos Safer Than Ephedrine Alone - Researcher

This article was originally published in The Tan Sheet

Executive Summary

Combining ephedrine alkaloids with caffeine may actually diminish the potential adverse effects of taking ephedrine alone, suggested Arne Astrup, MD/PhD, University of Copenhagen, Denmark, at a Public Health Service meeting on the safety of ephedra supplements.

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Ephedrine Alkaloid Sensitivity Study Urged By Researchers Boozer, Daly

A large, case-control study may be necessary to determine whether some people have unusually high sensitivity to the potential adverse effects of ephedrine alkaloids, researchers say in the May issue of the International Journal of Obesity

Ephedra studies

The Ephedra Education Council has assembled a panel of researchers to study the supplement ingredient's safety profile in light of FDA's recent AER review, the industry group announces July 25. EEC charges FDA's approach to ephedra safety "has serious scientific limitations," echoing past comments by Metabolife and the General Accounting Office (1"The Tan Sheet" Aug. 9, 1999, p. 3). The council has asked FDA that the panel, chaired by Stephen Kimmel, MD, University of Pennsylvania, be permitted to present its findings at the Aug. 8 public meeting on ephedra (2"The Tan Sheet" June 12, In Brief). Metabolife is among the sponsors of a safety study conducted by Carol Boozer, St. Lukes-Roosevelt Hospital Center, New York City, who is evaluating data and will attend the public meeting

Ephedra meeting

HHS Office on Women's Health to hold a public meeting on safety of ephedrine alkaloid-containing dietary supplements beginning Aug. 8, CFSAN says in a "Dear Colleagues" letter June 8. The meeting, to be held in the Washington, D.C. area, will last for two or three days. A Federal Register notice will provide specific scientific issues to be addressed; possible regulatory actions are not on the agenda. The meeting announcement will be posted on OWH's Web site (www.4woman.gov) on or about June 26. FDA has extended until July 3 the deadline for submitting new usage data and scientific evidence on ephedrine alkaloid-containing supplements; post-meeting comments will be accepted until Sept. 30 (1"The Tan Sheet" May 15, In Brief)

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