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E-Cigarettes' Appeal For Smoking Cessation Cooled By Risk Questions

Executive Summary

E-cigarette use among people with cancer increased from 8.5% in 2014 to 10.7% in 2017, with the greatest increase among people younger than 50, according to a JAMA Oncology study. A recently NEJM study also questions safety of growing dependence on e-cigarettes by people trying to quit smoking.

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Long-term E-cigarette Use Could Spark More Smoking, French Study Suggests

Research in JAMA Internal Medicine studied "longitudinal associations between [e-cigarette] use and tobacco smoking patterns in a large population-based cohort study" and found use was associated with reduction in smoking and an increased probability of smoking cessation. But the researchers saw that e-cigarette users who quit tobacco "tended to relapse to smoking more frequently than" former smokers who didn't use e-cigarettes.

E-cigarettes' Future Generates Questions, Not Their Efficacy For Smoking Cessation

FDA has made clear since e-cigarette sales emerged that they're not approved for labeling as products to help consumers stop using combustible tobacco. Agency also has acted on concerns about products' safety and appeal of flavored nicotine to minors. But likelihood of sales in US ending, not whether products help smokers quit, was discussed at FDLI conference.

Nicotine Poisoning Seizures Darken Cloud Around E-Cigarettes' NRT Potential

FDA for several years has noted opportunity for e-cigarettes and other electric nicotine delivery systems products to help adult smokers switch to a potentially less harmful form of nicotine delivery. "But we’ve also been clear that, even for adults, e-cigarettes are not risk free," says FDA Commissioner Gottlieb and Principal Deputy Commissioner Abernethy. Most seizures reported by youth and young adult e-cigarette users.

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