IFRA’s 49th Amendment To Safety Standards Coming Soon With QRA2 Updates
Notification may come within weeks for the 49th Amendment to the International Fragrance Association’s Code of Practice, which will update safe use standards for fragrance materials based on a revised quantitative risk assessment framework that uses a new aggregate exposure model for dermal sensitizers, among other changes. IFRA has been working closely on the issue of fragrance allergens with the European Commission.
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The International Fragrance Association has given its ingredient safety standards a major overhaul based on a new methodology that accounts for aggregate exposure and an updated Quantitative Risk Assessment model for dermal sensitization.
EU sources update Rose Sheet on contentious initiatives to cement the Commission’s pathway for banning carcinogenic, mutagenic or reprotoxic substances in cosmetics and to promote fragrance allergen awareness and risk management.
The Scientific Committee on Consumer Safety is not swayed by Cosmetic Europe's updated data submission suggesting that methylisothiazolinone can be safely used to preserve cosmetic products in concentrations as high as 100 ppm, taking issue with industry's Quantitative Risk Assessment model for dermal sensitization and tests cited in the trade group's calculations. The committee stands by its position that MI is unsafe for use in leave-on cosmetics and should be restricted to 15 ppm in rinse-off products.