Latest From David Wild
Building a narrow set of products and services that provide reliable and consistent revenue is a perfectly sound business strategy and one that sustains many biotech companies. But for the hungrier, like Twist Bioscience, Inc., a strategy of ongoing disruption and evolution has been more appealing and indeed is generating significant growth. Emily Leproust, Twist’s CEO, spoke with In Vivo about what it means to follow a value-added business strategy.
The cost of rare diseases to patients and society at large is 10 times higher than for many of the biggest mass market diseases combined. With 95% of rare diseases lacking a treatment or cure, there is an economic imperative for policymakers to keep encouraging pharmaceutical companies to develop more orphan drug treatments. In Vivo looks at the US and EU regulatory impetus to keep rare diseases open for innovation.
Rare disease treatments have been increasingly attractive targets for investment, but clinical trials of these agents are laden with unique challenges, not least of which is that there are by definition small and possibly disparately located patient populations. However, by cultivating relationships with patient organizations and carefully designing studies, companies in the rare disease space are proving they can overcome logistical hurdles.
Despite a raft of measures to prevent substandard or falsified (SF) medicines from reaching individuals, these medicines proliferated with the growth of e-commerce during the COVID-19 pandemic. The problem requires multistakeholder counter efforts, and for providers and patients to change their behaviors.
Acquisitions of early-stage assets, biotech platforms and capabilities like AI are the way to faster growth for pharma companies, as Accenture’s Petra Jantzer told In Vivo. However, changing the focus of M&A away from conventional late-stage assets requires significant shifts in corporate and R&D culture.
Bucking Convention, AavantiBio Co-Founder Marries Clinical Physical Therapy with Gene Therapy Research
There is no single road to leadership in biotech, as In Vivo Rising leader Manuela Corti demonstrates. The physical therapist shares her passion for treating neuromuscular disorders, the urgency of commercializing gene therapy treatment for these diseases, and the value of infusing the work environment with some fun.