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Warner Chilcott PLC

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Apellis’s pegcetacoplan – approved for two other indications – will not go forward in amyotrophic lateral sclerosis after a Phase II failure, two days after Wave Life made a similar call in the neurodegenerative disease.

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The US firm’s lead antibody oligonucleotide conjugate candidate has improved muscle strength and mobility in an early muscular dystrophy trial but some experts are disappointed by dose-specific data and a serious adverse event.

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The antibody-drug conjugate field is beginning to reach its full potential and big pharma’s attention has been caught.

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  • Pharmaceuticals
    • Generic Drugs
    • Drug Delivery
      • Topical Delivery
  • Other Names / Subsidiaries
    • Galen Holdings PLC
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