High Retinol Users’ Hip Fracture Rate Cracked By HRT
This article was originally published in The Tan Sheet
Executive Summary
High retinol intake doubles hip fracture risk in postmenopausal women not taking hormone-replacement therapy, researchers report in the Jan. 2 issue of the Journal of the American Medical Association
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Supplementation and food fortification with vitamin A may be harmful in Western countries where "life expectancy is high and the prevalence of osteoporosis is increasing," a Dutch researcher says in an editorial in the Jan. 23 New England Journal of Medicine
Research In Brief
Folic acid & colon cancer: Individuals with a family history of colon cancer "who use multivitamin supplements for >5 years may decrease their risk of colon cancer by almost 50%," researchers report in the March Cancer Epidemiology, Biomarkers & Prevention. Charles Fuchs, Dana-Farber Cancer Institute, et al., suggest "the influence of multivitamin supplements on the familial risk of colorectal cancer appears to principally reflect the folic acid content of multivitamins." Researchers found that among women who reported a family history of colon cancer, those who consumed more than 400 mcg folate per day were 52% less likely to have colon cancer than women who consumed 200 mcg or less per day. Fuchs et al. analyzed food frequency questionnaires and medical records of 88,758 women from the Nurses' Health Study...
Vitamin A Upper Limit Set For First Time By IoM's Food & Nutrition Board
The Institute of Medicine's Food & Nutrition Board announced vitamin A upper intake limits for the first time Jan. 9, setting the maximum safe intake at 3,000 mcg per day for both men and women.