In vitro dermal corrosivity tests
This article was originally published in The Rose Sheet
Executive Summary
Final recommended minimum performance standards for membrane barrier, human skin model and skin and transcutaneous electrical resistance assays are now available, the National Toxicology Program's National Institutes of Environmental Health Sciences announces in a May 28 Federal Register 1notice. NTP's Interagency Coordinating Committee on the Validation of Alternative Methods reviewed and recommended proposed standards, which are based on four in vitro assays - Corrositex, EpiSkin, EpiDerm and the rat skin transcutaneous electrical resistance assay - last July (2"The Rose Sheet" July 7, 2003, p. 5). The final recommendations and the four in vitro tests will now be forwarded to federal agencies, the notice states. The standards are available at 3http://iccvam.niehs.nih.gov/...